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2019
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Reaction of ribulose biphosphate carboxylase/oxygenase assembled on a DNA scaffold

Dinh, H; Nakata, E.; Lin, P.; Saimura, M.; Ashida, H.; Morii, T.
Bioorg. Med. Chem. 2019, 22, 115120
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Protein adaptors assemble functional proteins on DNA scaffolds

Ngo, T.; Dinh, H.; Nguyen, T.M.; Liew, F-F.; Nakata, E.; Morii, T.
Chem. Commun. 2019, 55, 12428-12446
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Rational design of a DNA sequence-specific modular protein tag by tuning the alkylation kinetics

Nguyen, T.M.; Nakata, E.; Zhang, Z.; Saimura, M.; Dinh, H.; Morii, T.
Chem. Sci. 2019, 10, 9315-9325
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Contribution of Coiled-Coil Assembly to Ca(2+)/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes

Polat, O.K.; Uno, M.; Maruyama, T.; Tran, H.N.; Imamura, K.; Wong, C.F.; Sakaguchi, R.; Ariyoshi, M.; Itsuki, K.; Ichikawa, J.; Morii, T.; Shirakawa, M.; Inoue, R.; Asanuma, K.; Reiser, J.; Tochio, H.; Mori, Y.; Mori, M.X.
J. Am. Soc. Nephrol. 2019, 30(9), 1587-1603.
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Nanometer Accuracy in Cryogenic Far-Field Localization Microscopy of Individual Molecules

Furubayashi, T.; Ishida, K.; Kashida, H.; Nakata, E.; Morii, T.; Matsushita, M.; Fujiyoshi, S.
J. Phys. Chem. Lett. 2019, 10, 5841-5846.
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DNA binding adaptors to assemble proteins of interest on DNA scaffold

Nakata, E.; Dinh, H.; Nguyen, T.M.; Morii, T.
Methods Enzymol. 2019, 617, 287-322.
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Highly selective dual sensing of ATP and ADP using fluorescent ribonucleopeptide sensors

Nakano, S.; Shimizu, M.; Dinh, H.; Morii, T.
Chem. Commun. 2019, 55(11), 1611-1614.
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Covalent Bond Formation by Modular Adaptors to Locate Multiple Enzymes on a DNA Scaffold

Nakata, E.; Nakano, S.; Rajendran, A.; Morii, T.
Kinetic Control in Synthesis and Self-Assembly 2019, pp.163-183. (ISBN 978-0-12-812126-9)
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2018

DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels

Kurokawa, T.; Kiyonaka, S.; Nakata, E.; Endo, M.; Koyama, S.; Mori, E.; Tran, N.H.; Dinh, H.; Suzuki, Y.; Hidaka, K.; Kawata, M.; Sato, C.; Sugiyama, H.; Morii*, T.; Mori*, Y.
Angew. chem. Int. Ed. 2018, 130, 2616-2621.
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効率的な多段階酵素反応を実現する分子コンビナート

中田栄司・森井 孝
バイオサイエンスとインダストリー vol.76 No.1 (2018)
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想いをつなぐ−生物の機能を化学で理解する

森井 孝
化学と工業 vol.71 No.2 (2018)
※コラム「私の自慢」
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2017

A diversity-oriented library of fluorophore-modified receptors constructed from a chemical library of synthetic fluorophores

Nakano, S.; Tamura, T.; Das, R. K.; Nakata, E.; Chang, Y.-T.; Morii, T.
ChemBioChem 2017, 18, 2212-2216.
→More Detail DOI: 10.1002/cbic.201700403

Design of Modular Protein-Tags for the Orthogonal Covalent Bond Formation at Specific DNA Sequences

Nguyen, T. M.; Nakata, E.; Saimura, M.; Dinh, H.; Morii, T.
J. Am. Chem. Soc. 2017, 139, 8487-8496.
→More Detail DOI: 10.1021/jacs.7b01640
日本語版プレスリリース →IAE-HP →PDF

※ 本論文の寄稿記事がAcademist Journalに掲載されました。
酵素を“1分子ずつ”狙った場所に配置する
-多段階反応を効率的に進行させる分子コンビナートをつくる
中田 栄司・森井 孝
2017年7月14日付研究コラム

Construction of a library of structurally diverse ribonucleopeptides with catalytic groups.

Tamura, T.; Nakano, S.; Nakata, E.; Morii, T.
Bioorg. Med. Chem. 2017, 25, 1881-1888.
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(review) A Bioorganic Chemistry Approach to Understanding Molecular Recognition in Protein-Nucleic Acid Complexes

Morii, T.
Bull. Chem. Soc. Jpn. 2017, 90, 1309-1317.
→More Detail DOI: 10.1246/bcsj.20170273

(review) Nucleic acids-templated enzyme cascades

Rajendran, A.; Nakata, E.; Nakano, S.; Morii, T.
ChemBioChem 2017, 18, 696-716.
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This review was selected as "ChemBioChem Readers‘ Choice 2019"
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DNA折り紙

森井 孝
高分子  2017, 66, 107.
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若手研究者からのメッセージ

中田栄司
バイオテクノロジー部会 NEWS LETTER 2017, 20, 7.
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ナノレベル間隔で異なる酵素を並べる!
─複雑な多段階反応を可能にする分子コンビナートへの挑戦─

中田栄司・森井 孝
月刊 化学 2017年11月号
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巻頭言「創造の動機」

森井 孝
生体関連部会 NEWS LETTER vol.32, No.1, (2017.6.19)
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2016

Spatially Organized Enzymes Drive Cofactor-Coupled Cascade Reactions.

Ngo, T. A.; Nakata, E.; Saimura, M.; Morii, T.
J. Am. Chem. Soc. 2016, 138, 3012-3021.
※This paper was introduced as "Virtual Issue on Engineered Biomolecular Catalysts" on ACS web site (→Link)
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Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives.

Nakata, E.; Yukimachi, Y.; Uto, Y.; Hori, H.; Morii T.
Sci. Tech. Adv. Mater. 2016, 17, 431-436.
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自己集合を利用した蛍光プローブのユニークな活用法
−洗浄操作を必要としない細胞内レシオイメージングへの応用−

中田栄司
バイオマテリアル  2016, 34, 198-203.
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DNAナノ構造体に酵素を配置した分子スイッチボード

中田栄司
生体機能関連化学部会 NEWS LETTER  2016, Vol.31, No.3.
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2015
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Validating subcellular thermal changes revealed by fluorescent thermosensors.

Kiyonaka, S.; Sakaguchi, R.; Hamachi, I.; Morii, T.; Yoshizaki, T.; Mori, Y.
Nature Methods 2015, 12, 801-802.
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A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds.

Nakata, E.; Dinh, H.; Ngo, T. A. ; Saimura, M.; Morii, T.
Chem. Commun. 2015, 51, 1016-1019.
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Self-Assembled Fluorescent Nanoprobe for the Detection of Fluoride Ions in Aqueous Solutions.

Nakata, E.; Nazumi, Y.; Yukimachi, Y.; Uto, Y.; Hori, H.; Morii, T.
Bull. Chem. Soc. Jpn., 2015, 88, 327-329.
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2014

Phosphorylation regulates fibrillation of an aggregation core peptide in the second repeat of microtubule-binding domain of human tau.

Inoue, M.; Kaida, S.; Nakano, S.; Annoni, C.; Nakata, E.; Konno, T.; Morii, T.
Bioorg. Med. Chem. 2014, 22, 6471-6480.
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Peptidosteroid Tweezers Revisited: DNA Binding Through an Optimised Design.

Carrette, L. L.; Morii, T.; Madder, A.
Eur. J. Org. Chem. 2014, 2883-2891.
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A protein adaptor to locate a functional protein dimer on molecular switchboard.

Ngo, T. A.; Nakata, E.; Saimura, M.; Kodaki, T.; Morii, T.
Methods 2014, 67, 142-150.
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A novel strategy to design latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives.

Nakata, E.; Yukimachi, Y.; Nazumi, Y.; Uwate, M.; Maseda, H.; Uto, Y.; Hashimoto,T.; Okamoto, Y.; Hori, H.; Morii, T.
RSC Advances 2014, 4, 348-357.
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細胞内レシオ型蛍光pHプローブ開発のための自己集合化ナノプローブの合理的設計戦略

中田栄司
和光純薬時報  2014, 82, 6-8
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SNARF誘導体の自己集合化戦略に基づいた外部刺激応答性のレシオ型蛍光pHプローブの開発

中田栄司
ナノ学会会報  2014, 12, 51-56
2013
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Toxicity inspired cross-linking for probing DNA-peptide interactions.

Carrette, L. L.; Morii, T.; Madder, A.
Bioconjug. Chem. 2013, 24, 2008-2014.
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Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells.

Kiyonaka, S.; Kajimoto, T.; Sakaguchi, R.; Shinmi, D.; Omatsu-Kanbe, M.; Matsuura, H.; Imamura, H.; Yoshizaki, T.; Hamachi, I.; Morii, T.; Mori, Y.
Nat. Methods 2013, 10, 1232-1238.
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Simultaneous Detection of ATP and GTP by Covalently Linked Fluorescent Ribonucleopeptide Sensors.

Nakano, S.; Fukuda, M.; Tamura, T.; Sakaguchi, R.; Nakata, E.; Morii, T.
J. Am. Chem. Soc. 2013, 135, 3465-3473.
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A Peptide Nucleic Acid (PNA) Heteroduplex Probe Containing an Inosine-Cytosine Base Pair Discriminates a Single-Nucleotide Difference in RNA.

Matsumoto, K.; Nakata, E.; Tamura, T.; Saito, I.; Aizawa, Y.; Morii, T.
Chem. Eur. J. 2013, 19, 5034-5040.
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Arranging enzymes and receptors with nanometer-scale precision on molecular switchboards.

Ngo T. A.; Nakata, E.; Morii, T.
J. Biomol. Struct. Dyn. 2013, 31, 86
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2012
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Construction of ratiometric fluorescent sensors by ribonucleopeptides.

Annoni, C.; Nakata, E.; Tamura, T.; Liew, F. F.; Nakano, S.; Gelmi, M. L.; Morii, T.
Org. Biomol. Chem. 2012, 10, 8767-8769.
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Zinc finger proteins for site-specific protein positioning on DNA origami.

Nakata, E.; Liew, F. F.; Uwatoko, C.; Kiyonaka, S.; Mori, Y.; Katsuda, Y.; Endo, M.; Sugiyama, H.; Morii T.
Angew Chem. Int. Ed. 2012, 51, 2421-2424.
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Positional effects of phosphorylation on the stability and the morphology of tau-related amyloid fibrils.

Inoue, M.; Konno, T.; Tainaka, K.; Nakata, E.; Yoshida, H.; Morii, T.
Biochemistry 2012, 51, 1396-1406.
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Study on the Application of Furan Crosslinking at the Protein-DNA Interface.

Carrette, L. L. G.; Gattner, M.; Van den Begin, J.; Carell, T.; Morii, T.; Madder, A.
J. Pep. Sci. 2012, 18, S99.
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タンパク質ベースの蛍光バイオセンサー
ここまで進んだバイオセンシング・イメージング(分担執筆)

中田 栄司, 森井 孝
日本化学会 編著, 東京, 2012年11月
2011
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Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain.

Anraku, K.; Inoue, T.; Sugimoto, K.; Kudo, K.; Okamoto, Y.; Morii, T.; Mori, Y.; Otsuka, M.
Bioorg. Med. Chem. 2011, 19, 6833-6841.
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A ribonucleopeptide module for effective conversion of an RNA aptamer to a fluorescent sensor.

Liew, F. F.; Hayashi, H.; Nakano, S.; Nakata, E.; Morii, T.
Bioorg. Med. Chem. 2011, 19, 5771-5775.

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Construction of dopamine sensors by using fluorescent ribonucleopeptide complexes.

Liew, F. F.; Hasegawa, T.; Fukuda, M.; Nakata, E.; Morii, T.
Bioorg. Med. Chem. 2011, 19, 4473-4481.
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Facile conversion of RNA Aptamers to modular fluorescent sensors with tunable detection wavelengths.

Nakano, S.; Nakata, E.; Morii, T.
Bioorg. Med. Chem. Lett. 2011, 21, 4503-4506.
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Structural Aspects for the Recognition of ATP by Ribonucleopeptide Receptors.

Nakano, S.; Mashima, T.; Matsugami, A.; Inoue, M.; Katahira, M.; Morii, T.
J. Am. Chem. Soc. 2011, 133, 4567-4579.
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Design and synthesis of highly solvatochromic fluorescent 2'-deoxyguanosine and 2'-deoxyadenosine analogs.

Matsumoto, K.;Takahashi, N.; Suzuki, A.; Morii, T.; Saito, Y.; Saito, I.
Bioorg. Med. Chem. Lett. 2011, 21, 1275-1278.
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Selective assembly of photosynthetic antenna proteins into a domain-structured lipid bilayer for the construction of artificial photosynthetic antenna systems: structural analysis of the assembly using surface plasmon resonance and atomic force microscopy.

Sumino, A.; Dewa, T.; Kondo, M.; Morii, T.; Hashimoto, H.; Gardiner, AT.; Cogdell, RJ.; Nango, M.
Langmuir 2011, 27, 1092-1099.
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The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions.

Tanaka, N.; Morimoto, Y.; Noguchi, Y.; Tada, T.; Waku, T.; Kunugi, S.; Morii, T.; Lee, YF.; Konno, T; Takahashi, N.
J. Biol. Chem. 2011, ,286, 5584-5594.
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Recent progress in the construction methodology of fluorescent biosensors based on biomolecules.

Nakata, E.; Liew, F.F.; Nakano, S.; Morii, T.
"Biosensors Emerging Materials and Applications, Chapter 7", DOI: 10.5772/17724
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2010
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Design of environmentally sensitive fluorescent 2'-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probe.

Shinohara, Y.; Matsumoto, K.; Kugenuma, K,; Morii, T.; Saito, Y.; Saito, I.
Bioorg. Med. Chem. Lett. 2010, 20, 2817-2820.
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An in vitro fluorescent sensor reveals intracellular Ins(1,3,4,5)P4 dynamics in single cells.

Sakaguchi, R.; Tainaka, K.; Shimada, N.; Nakano, S.; Inoue, M.; Kiyonaka, S.; Mori, Y.; Morii, T.
Angew. Chem. Int. Ed. 2010, 49, 2150-2153.
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Design Strategies of Fluorescent Biosensors Based on Biological macromolecular Receptors.

Tainaka, K.; Sakaguchi, R.; Hayashi, H.; Nakano, S.; Liew, F.-F.; Morii, T.
Sensors 2010, 10, 1355-1376.
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2009
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Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.

Kiyonaka, S.; Kato, K.; Nishida, M.; Mio, K.; Numaga, T.; Sawaguchi, Y.; Yoshida, T.; Wakamori, M.; Mori, E.; Numata, T.; Ishii, M.; Takemoto, H.; Ojida, A.; Watanabe, K.; Uemura, A.; Kurose, H.; Morii, T. Kobayashi, T.; Sato, Y.; Sato, C.; Hamachi, I.; Mori, Y.
Proc. Natl. Acad. Sci. U S A 2009, 106, 5400-5405.
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The amyloid fibrillization of phosphorylated human tau core peptides.

Inoue, M.; Tainaka, K.; Hirata, A.; Konno, T.; Morii, T.
Trans. Mat. Res. Soc. Jpn. 2009, 34, 517-520.
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Development of A Fluorescent Ribonucleopeptide Sensor for Histamine.

Fukuda, M.; Hayashi, H.; Hasegawa, T.; Morii, T.
Trans. Mat. Res. Soc. Jpn. 2009, 34, 515-527.
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A single circularly permuted GFP sensor for inositol-1,3,4,5-tetrakisphosphate based on a split PH domain.

Sakaguchi, R.; Endoh, T.; Yamamoto, S.; Tainaka, K.; Sugimoto, K.; Fujieda, N.; Kiyonaka, S.; Mori, Y.; Morii, T.
Bioorg. Med. Chem. 2009, 17, 7381-7386.
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Design of extremely facile 3'- and 5'-ends free molecular beacons using C8 alkylamino substituted 2'-deoxyguanosine.

Matsumoto, K.; Shinohara, Y.; Numajiri, K.; Ishioroshi, S.; Morii, T.; Saito, Y.; Saito, I.
Nucleic Acids Symp. Ser. 2009, 53, 141-142.
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Covalently linked fluorescent ribonucleopeptide sensors.

Fukuda, M.; Liew, F-F.; Morii, T.
Nucleic Acids Symp. Ser. 2009, 53, 257-258.
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Structural aspects for the function of ATP-binding ribonucleopeptide receptors.

Fukuda, M., Fong-Fong, L., Morii, T.
Nucleic Acids Symp. Ser. 2009, 53, 257-258.
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Structural analysis of ribonucleopeptide aptamer against ATP.

Mashima, T.; Matsugami, A.; Nakano, S.; Inoue, M.; Fukuda, M.; Morii, T.; Katahira, M.
Nucleic Acids Symp. Ser. 2009, 53, 267-268.
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A Modular Strategy for Development of RNA-Based Fluorescent Sensors.

Fukuda, M.; Hasegawa, T.; Hayashi, H.; Morii, T.
"Combinatorial methods for chemical and biological sensors." Chapter 10, pp. 249-269, R. A. Potyrailo and V. M. Mirsky (Eds.), Springer, 2009.
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2008
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Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques. 

Anraku, K.; Inoue, T.; Sugimoto, K.; Morii, T.; Mori, Y.; Okamoto, Y.; Otsuka, M.
Org. Biomol. Chem. 2008, 6, 1822-1830.
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Context-dependent fluorescence detection of a phosphorylated tyrosine residue by a ribonucleopeptide.

Hasegawa, T.; Hagiwara, M.; Fukuda, M.; Nakano, S.; Fujieda, N.; Morii, T.
J. Am. Chem. Soc. 2008, 130, 8804-8812.
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Charge-pairing mechanism of phosphorylation effect upon amyloid fibrillation of human tau core peptide.

Inoue, M.; Hirata, A.; Tainaka, K.; Morii, T.; Konno, T.
Biochemistry. 2008, 47, 11847-11857.
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Construction of a stable functional ribonucleopeptide complex by the covalent linking method.

Fukuda, M.; Nakano, S.; Tainaka, K.; Fujieda, N.; Morii T.
Nucleic Acids Symp. Ser (Oxf). 2008, 52, 195-196.
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Selective recognition of a tetra-amino-acid motif containing phosphorylated tyrosine residue by ribonucleopeptide.

Nakano, S.; Hasegawa, T.; Fukuda, M.; Fujieda, N.; Tainaka, K.; Morii, T.
Nucleic Acids Symp. Ser. (Oxf). 2008, 52, 199-200.
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Development of ribonucleopeptide-based fluorescent sensors for biologically active amines based on the stepwise molding strategy.

Tainaka, K.; Hasegawa, T.; Fukuda, M.; Nakano, S.; Fujieda, N.; Morii, T.
Nucleic Acids Symp. Ser. (Oxf). 2008, 52, 201-202.
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細胞内シグナル伝達物質リアルタイム検出用プローブ

森井 孝
「バイオインダストリー」、Vol. 25 (2), 7-14, (2008).
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RNA-タンパク質複合体の分子進化を利用したアプタマーとセンサーの開発

福田将虎、森井 孝
生物物理、Vol. 48, 239-242 (2008).
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2007
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Synergic action of polyanionic and non-polar cofactors in fibrillation of human islet amyloid polypeptide.

Konno, T.; Oiki S.; Morii T.
FEBS Lett. 581, 1635-1638 (2007).
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Amyloid-forming propensity of the hydrophobic non-natural amino acid on the fibril-forming core peptide of human tau.

Hirata, A.; Sugimoto, K.; Konno, T.; Morii, T.
Bioorg. Med. Chem. Lett. 17, 2971-2974 (2007).
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Stepwise functionalization of ribonucleopeptides: optimization of the response of fluorescen ribonucleopeptide sensors for ATP.

Hasegawa, T.; Hagihara, M.; Fukuda, M.; Morii; T.
Nucleosides Nucleotides & Nucleic Acids 2007, 26, 1277-1281.
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Structure-based design of fluorescent biosensors from ribonucleopeptide complexes.

Hayashi, H.; Inoue, M.; Morii, T.
Nucleic Acids Symp. Ser. 2007, 51, 95-96.
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Controlling a substrate-binding geometry of ribonucleopeptide receptor.

Fukuda, M.; Nakano, S.; Morii T.
Nucleic Acids Symp. Ser. 2007, 51, 421-422.
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Construction of ribonucleopeptide-based fluorescent sensors for biologically active amines.

Hasegawa, T.; Hayashi, H.; Morii, T.
Nucleic Acids Symp. Ser. 2007, 51, 423-424.
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Design of Ribonucleopeptide-based Receptors and Fluorescent Sensors.

Morii, T.
J. Biomol. Struct. Dynam. 2007, 24, 689.
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RNA-ペプチド複合体をもとにした機能性分子の創製

森井 孝 
「ゲノム化学:医学、分子生物学への応用と展開」化学フロンティア18, pp. 45-52,(2007)
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テーラーメイド蛍光センサーの開発

森井 孝
「化学工業、Vol. 58 (5), 38-43, (2007).
2006
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Nitric oxide activates TRP channels by cysteine S-nitrosylation.

Yoshida, T.; Inoue, R.; Morii, T.; Takahashi, N.; Yamamoto, S.; Hara, Y.; Tominaga, M.; Shimizu, S.; Sato, Y.; Mori, Y.
Nature Chem. Biol. 2006, 2, 596-607.
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A modular strategy for tailoring fluorescent biosensors from ribonucleopeptide complexes.

Hagihara, M.; Fukuda, M.; Hasegawa, T.; Morii T.
J. Am. Chem. Soc. 2006, 128, 12932-12940.
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ケミカルバイオロジーのツールとしての機能性ミニチュアタンパク質

森井 孝
化学工業、Vol. 57 (9), 8(656)-12(660), (2006).
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「ファージディスプレイ法を用いたセレクション (標的分子に結合する生体分子の作製)」

福田将虎、杉本健二、森井 孝
生命科学研究レター, 22, 24-29 (2006)
2005
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Stepwise Molding of a Highly Selective Ribonucleopeptide Receptor.

Sato, S.; Fukuda, M.; Hagihara, M.; Tanabe, Y.; Ohkubo, K.; Morii, T.
J. Am. Chem. Soc. 2005, 127, 30-31.
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A Ribonucleopeptide Receptor Targets Phosphotyrosine.

Hasegawa, T.; Ohkubo, M. K.; Yoshikawa, S.; Morii, T.
J. Surf. Sci. Nanotech. 2005, 3, 41-45.
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Covalent blocking of amyloid formation and protein aggregation by transglutaminase-catalyzed intra-molecular cross-linking.

Konno, T.; Morii, T.; Hirata, A.; Sato, S.; Naiki, H.; Oiki, S.; Ikura K.
Biochemistry 2005, 44, 2072-2079.
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Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1.

Hirata, A.; Ueno, M.; Aizawa, Y.; Ohkubo, K.; Morii, T.; Yoshikawa, S.
Bioorg. Med. Chem.2005, 13, 3107-3116.
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Paradoxical inhibition of protein aggregation and precipitation by transglutaminase-catalyzed intermolecular cross-linking.

Konno, T.; Morii, T.; Shimidzu, H.; Oiki, S.; Ikura, K.
J. Biol. Chem. 2005, 280, 17520-17525.
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Ribonucleopeptides recognize the phosphotyrosine residue.

Hasegawa, T.; Yoshikawa, S.; Morii T.
Nucleic Acids Res. Symp. Ser. 2005, 49, 79-80.
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Stepwise functionalization of ribonucleopeptide complexes to receptors and sensors.

Fukuda, M.; Tanabe, Y.; Morii, T.
Nucleic Acids Res. Symp. Ser. 2005, 49, 355-356.
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敬虔な生体高分子ファン? それとも・・・

森井 孝
RNA Network Newsletter, volume 3, number 2, 59-62, January 2005.
2004
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Ribonucleopeptides: functional RNA-peptide complexes.

Hagihara, M.; Hasegawa, T.; Sato, S.; Yoshikawa, S.; Ohkubo, K.; Morii, T.
Pep. Sci. 2004, 76, 66-68.
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Novel real time sensors to quantitatively assess in vivo inositol 1,4,5-trisphosphate production in intact cells.

Sugimoto, K.; Nishida, M.; Otsuka, M.; Makino, K.; Ohkubo, K.; Mori, Y.; Morii, T.
Cell. Chem. Biol. 2004, 11, 475-485.
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Design of sensing ribonucleopeptides for small ligands.

Hagihara, M.; Hasegawa, T.; Tanabe, Y.; Sato, S.; Yoshikawa, S.; Ohkubo, K.; Morii, T.
Nucleic Acids Res. Symp. Ser. 2004, 48, 33-34.
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Recent advances in biosensing second messengers.

Sugimoto, K.; Sakaguchi, R.; Mori, Y.; Morii, T.
Recent Res. Devel. Chem. 2004, 2, 73-89.
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タンパク質・核酸をもとにした機能性分子設計

森井 孝
生命化学研究レター No.16, 10-18, 2004年10月
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Ribonucleopeptide receptors.

Hagihara, M.; Hasegawa, T.; Sato, S.; Yoshikawa, S.; Ohkubo, K.; Morii, T.
Peptide Revolution: Genomics, Proteomics & Therapeutics. The Proceedings Of The 18Th American Peptide Symposium M. Chorev, p. 556-558, T. K. Sawyer, Ed., American Peptide Society (2004).
2003
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Functional Reassembly of a Split PH Domain.

Sugimoto, K.; Mori, Y.; Makino, K.; Ohkubo, K.; Morii, T.
J. Am. Chem. Soc. 2003, 125, 5000-5004.
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Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe.

Mori, M.; Konno, T.; Morii, T.; Nagayama, K.; Imoto, K.
Biochem. Biophys. Res. Commun. 2003, 307, 290-296.
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Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCg2 in B lymphocytes.

Nishida, N.; Sugimoto, K.; Hara, Y.; Mori, E.; Morii, T.; Kurosaki, T.; Mori, Y.
EMBO J. 2003, 22, 4677-4688.
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Design of a ribonucleopeptide biosensor.

Hagihara, M.; Hirata, A.; Ohkubo, K.; Morii, T.
Nucleic Acids Res. Suppl. 2003, 3, 193-194.
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Optimization of an ATP-binding ribonucleopeptide receptor.

Sato, S.; Hasegawa, T.; Hagihara, M.; Fukuda, M.; Ohkubo, K.; Morii, T.
Nucleic Acids Res. Suppl. 2003, 3, 239-240.
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Ribonucleopeptide receptors.

Morii, T.; Ohkubo K.; Yoshikawa S.
Biopolymers 2003, 71(3), 323.
2002
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Formation of a Fairly Stable Diazoate Intermediate of 5-Methyl-2'-deoxycytidine by HNO2 and NO, and Its Implication to a Novel Mutation Mechanism in CpG Site.

Suzuki, T.; Yamada, M.; Nakamura, T.; Ide, H.; Kanaori, K.; Tajima, K.; Morii,T.; Makino, K.
Bioorg. Med. Chem. 2002, 10, 1063-1067.
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A General Strategy to Determine a Target DNA Sequence of Short Peptide: Application to a D-Peptide.

Morii, T.; Tanaka, T.; Sato, S.; Hagihara, M.; Aizawa, Y.; Makino, K.
J. Am. Chem. Soc. 2002, 124, 180-181.
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A New Fluorescent Biosensor for Inositol Trisphosphate.

Morii, T.; Sugimoto, K.; Makino, K.; Otsuka, M.; Imoto, K.; Mori, Y.
J. Am. Chem. Soc. 2002, 124, 1139-1140.
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Structure-Based Design of a Leucine Zipper Protein with New DNA Contacting Region.

Morii, T.; Sato, S.; Hagihara, M.; Mori, Y.; Imoto, K.; Makino, K.
Biochemistry 2002, 41, 2177-2183.
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In Vitro Selection of ATP-binding Receptors Using a Ribonucleopeptide Complex.

Morii, T.; Hagihara, M.; Sato, S.; Makino, K.
J. Am. Chem. Soc. 2002, 124, 4617-4622.
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Chemical Approach to Untangle the Sequence-Specific DNA Binding by Proteins.

Sato, S.; Hagihara, M.; Sugimoto, K.; Morii, T.
Chem-Eur. J. 2002, 22, 5067-5071.
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A new strategy to determine the target DNA sequence of a short peptide.

Sato, S.; Honjyo, H.; Tsuji, S.; Hagihara, M.; Makino K.; Morii, T.
Nucleic Acids Res. Suppl. 2002, 2, 205-206.
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Sequence-specific DNA binding by short peptides.

Morii T.; Makino, K.
Advances in DNA Sequence Specific Agents, 2004, 4, 105-137.
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講演題目:折り紙でつくる化学コンビナート

第9回京都大学附置研究所・センターシンポジウム:京都からの提言〜21世紀の日本を考える(2014年3月15日仙台国際センター) にて森井 孝教授が講演をされました。
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講演題目:体の中にある分子コンビナート

第32回品川セミナー(2013年1月11日)にて森井 孝教授が講演をされました。
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