Discovery of a common method for thermostabilizing many G-protein coupled receptors (GPCRs), important drug targets ―Contribution to new solution of three-dimensional structures of multiple GPCRs―
Research Topics / 研究トピックス
An article written by R. Suno, S. Lee, S. Maeda, S. Yasuda, K. Yamashita, K. Hirata, S. Horita, M.S. Tawaramoto, H. Tsujimoto, T. Murata, M. Kinoshita, N. Vaidehi, M. Yamamoto, B.K. Kobilka, S. Iwata, T. Kobayashi was published in Nature Chemical Biology
Title; Structural Insights into the Subtype Selective Antagonist Binding to the M2 Muscarinic Receptor
DOI: 10.1038/s41589-018-0152-y
2018, Nov. 12
An article written by Y. Toyoda, K. Morimoto, R. Suno, S. Horita, K. Yamashita, K. Hirata, Y. Sekiguchi, S. Yasuda, M. Shiroishi, T. Shimizu, Y. Urushibata, Y. Kajiwara, T. Inazumi, Y. Hotta, H. Asada, T. Nakane, Y. Shiimura, T. Nakagita, K. Tsuge, S. Yoshida, T. Kuribara, T. Hosoya, Y. Sugimoto, N. Nomura, M. Sato, T. Hirokawa, M. Kinoshita, T. Murata, K. Takayama, M. Yamamoto, S. Narumiya, S. Iwata, T. Kobayashi was published in Nature Chemical Biology
Title; Ligand Binding to Human Prostaglandin E Receptor EP4 at the Lipid-Bilayer Interface
DOI: 10.1038/s41589-018-0131-3
2018, Dec. 3
Assembly Science Research Section Complex Energy Processes Research Section